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Image Search Results
Journal: Frontiers in Reproductive Health
Article Title: Spatiotemporal dynamics of spermatogenesis: insights from high-resolution spatial transcriptomics and pseudotime trajectories in mouse testes
doi: 10.3389/frph.2025.1747902
Figure Lengend Snippet: Salus-STS high-resolution spatial transcriptomics enables effective cell identification at the subcellular level. (A) Schematics illustrating of the study. (B) Results of cell segmentation via the Salus Cellbins Algorithm. (C–F) Distributions and medians (red text in the figures) of the area (in pixel 2 ) (C) , UMI counts (D) , gene numbers (E) , and proportions of mitochondrial UMIs (F) of segmented cellbins.
Article Snippet: In this study, we used
Techniques:
Journal: Frontiers in Reproductive Health
Article Title: Spatiotemporal dynamics of spermatogenesis: insights from high-resolution spatial transcriptomics and pseudotime trajectories in mouse testes
doi: 10.3389/frph.2025.1747902
Figure Lengend Snippet: Cellbin-based analysis enables accurate identification of distinct cell types in the mouse testis. (A) RCTD-annotated distinct cell types and their proportions. (B) UMAP visualization of the Salus-STS Cellbin data with scRNA-Seq data. (C) Spatial distribution of distinct cell types in the mouse testis. (D) Integrated distribution map of cell distributions in the mouse testis. (E) Markers of distinct cell types and their expression levels. Scaled expression: the average expression level scaled across genes to eliminate the effect of total expression level differences among genes. Percentage: for each cell type, the percentage of cellbins that express the specific gene out of all cellbins of the same type.
Article Snippet: In this study, we used
Techniques: Expressing
Journal: Frontiers in Reproductive Health
Article Title: Spatiotemporal dynamics of spermatogenesis: insights from high-resolution spatial transcriptomics and pseudotime trajectories in mouse testes
doi: 10.3389/frph.2025.1747902
Figure Lengend Snippet: High-resolution spatial transcriptomics uncovers spatiotemporal markers of spermatogenesis. (A) Pseudotime trajectory analysis. (B) Randomly selected seminiferous tubules. (C,D) Top 6 genes with expression levels positively (C) and negatively (D) correlated with the axis from the tubule basement membrane (epithelium) to the lumen center respectively.
Article Snippet: In this study, we used
Techniques: Expressing, Membrane
Journal: Frontiers in Reproductive Health
Article Title: Spatiotemporal dynamics of spermatogenesis: insights from high-resolution spatial transcriptomics and pseudotime trajectories in mouse testes
doi: 10.3389/frph.2025.1747902
Figure Lengend Snippet: Salus-STS high-resolution spatial transcriptomics enables effective cell identification at the subcellular level. (A) Schematics illustrating of the study. (B) Results of cell segmentation via the Salus Cellbins Algorithm. (C–F) Distributions and medians (red text in the figures) of the area (in pixel 2 ) (C) , UMI counts (D) , gene numbers (E) , and proportions of mitochondrial UMIs (F) of segmented cellbins.
Article Snippet: In this study, we used Salus-STS high-resolution
Techniques:
Journal: Frontiers in Reproductive Health
Article Title: Spatiotemporal dynamics of spermatogenesis: insights from high-resolution spatial transcriptomics and pseudotime trajectories in mouse testes
doi: 10.3389/frph.2025.1747902
Figure Lengend Snippet: Cellbin-based analysis enables accurate identification of distinct cell types in the mouse testis. (A) RCTD-annotated distinct cell types and their proportions. (B) UMAP visualization of the Salus-STS Cellbin data with scRNA-Seq data. (C) Spatial distribution of distinct cell types in the mouse testis. (D) Integrated distribution map of cell distributions in the mouse testis. (E) Markers of distinct cell types and their expression levels. Scaled expression: the average expression level scaled across genes to eliminate the effect of total expression level differences among genes. Percentage: for each cell type, the percentage of cellbins that express the specific gene out of all cellbins of the same type.
Article Snippet: In this study, we used Salus-STS high-resolution
Techniques: Expressing